I have company computers that were delivered (in 2006) with 512 MB of RAM. These are low-end computers with 2 memory slots with 256 MB modules of DDR2 in each.
Crucial (
http://www.crucial.com/systemscanner/index.aspx - IE only) says
Although the memory can be installed one module at a time, the best performance comes from using matched pairs of modules.
I can buy 1 GB modules for about 5% more per GB than 2 GB. Is it worthwhile to throw away that other 256 MB and have a matched 2 GB rather than an unmatched 2.25 GB? I'm expecting such a performance improvement anyway that I might as well save $40 across the office and upgrade another machine.